The most commonly reported side effects include nausea, diarrhea, constipation, and abdominal pain
But if you are overweight or have mild obesity without associated diseases, the risks may or may not outweigh the benefits
(2023) 15:e34572
Patients with other conditions, including systemic lupus erythematosus, psoriatic arthritis and rheumatoid arthritis, could be potential benefactors as well
For the primary composite outcome and secondary hierarchical outcomes, the threshold for two-sided statistical significance was set to 0.0322 (one-sided level 0.00161) using Lan-DeMets alpha spending function, which allows to adjust significance levels as data were reviewed for the interim analysis, reducing the chance of false positive results
Retatrutide is an investigational triple-receptor medication being studied for GIP, GLP-1, and glucagon receptor activity